SARS-CoV-2 Mpro-IN-44

SKU: orb3027915

Description

SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum inhibitor of the main protease (Mpro) for coronaviruses. It exhibits inhibitory activity against several high-risk coronaviruses, including SARS-CoV-2 and PEDV, with an IC50 of less than 0.6 μM. The broad inhibition of coronaviruses by SARS-CoV-2 Mpro-IN-44 is achieved through enhanced interaction with conserved sites of Mpro. This compound is a potential candidate for the development of antiviral drugs against coronaviruses.

Research Area

Infectious Disease & Virology

Images & Validation

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Key Properties

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CAS Number	3020713-53-2
MW	665.48
Formula	C₂₉H₁₉Cl₂FN₈O₄S
SMILES	C(N1\C(=N\C2=CC=3C(C=C2Cl)=NN(C)C3)\NC(=O)N(CC=4C(=O)NC=CC4)C1=O)C5=C(OC=6SC(C#N)=CC6)C=C(F)C(Cl)=C5
Target	Virus Protease,SARS-CoV

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Virus Protease,SARS-CoV

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