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SARS-CoV-2 Mpro-IN-4

SKU: orb1744899

Description

SARS-CoV-2 Mpro-IN-4 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL), with inhibition concentrations (IC50) of 900 nM and 60 nM, respectively. It effectively blocks SARS-CoV-2 replication in hACE2-expressing A549 cells, demonstrating antiviral activity with an IC50 value of 8.2 nM.

Images & Validation

Key Properties

MW534.65
FormulaC30H38N4O5
SMILESCCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)NC
TargetVirus Protease,SARS-CoV,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

SARS-CoV-2 Mpro-IN-4 (orb1744899)

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