SARS-CoV-2-IN-46

SKU: orb1819094

Description

SARS-CoV-2-IN-46 is a small molecule compound designed to inhibit SARS-CoV-2. It serves as a valuable research tool for in vitro antiviral studies, aiding in the investigation of coronavirus replication mechanisms and the discovery of novel therapeutic agents.

Research Area

Infectious Disease & Virology

Key Properties

• MW: 318.07
• Purity: 97.15% (May vary between batches)
• Formula: C₁₇H₁₂F₂O₄
• SMILES: COC1=CC=C(/C=C2\OC3=CC(OC(F)F)=CC=C3C2=O)C=C1
• Target: SARS-CoV
• Solubility: DMSO:60 mg/mL (188.64 mM)

Bioactivity

• Target IC50:
  Calu3 (cells):0.9 μM(EC50)
• In Vitro:
  SARS-CoV-2-IN-46 (Compound 8w) (1-10 μM) inhibits SARS-CoV-2 replication by over 50% in Calu-3 cells and demonstrates low toxicity at 250 μM over 72 hours in the same cell line.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SARS-CoV-2, SARSCoV2IN46, SARS-CoV-2-IN-46, SARSCoV

Compound Identifiers

PubChem CID

169553431