SARS-CoV-2 (COVID-19) S1 protein

• Catalog Number: orb640169
• Category: Proteins
• Description: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
• Reactivity: Virus
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 101.5 kDa
• Target: Spike S1
• Protein Sequence: QHD43416.1
• Source: SARS-CoV-2 S1 protein, Fc Tag (orb640169) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1).
• Expression System: HEK293
• Expression Region: Val 16 - Arg 685
• Endotoxins: 1.0 EU per μg
• NCBI: QHD43416.1
• Storage: -20°C
• Buffer/Preservatives: Tris, Glycine and NaCl, pH7.5
• Alternative names: Spike,S1 protein,Spike glycoprotein Subunit1,S gly
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 101.5 kDa. The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.