SARS-CoV-2 (COVID-19) Alpha Variant (B.1.1.7, UK) Spike S1 (RBD) Recombinant Protein

• Catalog Number: orb1231047
• Category: Proteins
• Description: SARS-CoV-2 (COVID-19) Alpha Variant (B.1.1.7, UK) Spike S1 (RBD) Recombinant Protein
• Concentration: 1mg/ml after reconstitution.
• Form/Appearance: Lyophilized
• Purity: ≥95% (SDS-PAGE)
• MW: ~60kDa (SDS-PAGE)
• Target: S
• UniProt ID: P0DTC2
• Protein Sequence: Receptor-binding domain (RBD) of SARS-CoV-2 Spike protein S1 (aa 319-541) containing the mutation N501Y is fused to the N-terminus of the Fc region of human IgG1.
• Source: HEK293 cells
• Biological Activity: Binds to human ACE2.
• NCBI: QHD43416.1
• Storage: Short Term StorageL: +4°C, Long Term Storage: -20°C, Handling Advice: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. For maximum product recovery after thawing, centrifuge the vial before opening the cap. Use/Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Buffer/Preservatives: Lyophilized. Contains PBS.
• Alternative names: 2019-nCoV Spike Protein S1 (RBD); Spike Receptor B
• Note: For research use only
• Expiration Date: 6 months from date of receipt.

SARS-CoV-2 Spike Protein S1 (RBD):Fc (human) (rec.) (B.1.1.7 Variant, UK) binds to the receptor ACE2 (human) (rec.) slightly stronger than SARS-CoV-2 Spike Protein S1 (RBD):Fc (human) (rec.) (WT).