SAR502250

SKU: orb1694512

Description

SAR502250 is a potent, brain-penetrant, and orally active inhibitor of GSK-3β, demonstrating an IC50 of 12 nM. It shows antidepressant-like effects in preclinical models and is investigated for Alzheimer's disease, with studies exploring its neuroprotective mechanisms in vitro and in vivo.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 503860-57-9
• MW: 367.38
• Formula: C₁₉H₁₈FN₅O₂
• SMILES: Cn1c(nc(cc1=O)-c1ccncn1)N1CCO[C@H](C1)c1ccc(F)cc1
• Target: GSK-3,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56589672