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SAR247799

SAR247799

Catalog Number: orb2944227

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Product Properties
Catalog Numberorb2944227
CategorySmall Molecules
DescriptionSAR247799 (S1P1 agonist 3) is a selective and G-protein-biased S1P1 agonist that activates downstream G-protein signaling pathways more preferentially than β-blocker proteins and internalized signaling pathways, activates S1P 1 on endothelial cells without causing receptor desensitization, and protects the endothelium without affecting lymphocyte populations, and can be used to study type 2 diabetes, endothelial dysfunction and vascular hyperpermeability.
TargetS1P Receptor,LPL Receptor
MW425.82
CAS Number1315311-14-8
FormulaC21H16ClN3O5
SMILESO=C(O)COC=1C(=CC(=CC1C)C2=NC3=CN=C(N=C3O2)OC=4C=CC=C(Cl)C4)C
Storage-20°C
Research AreaPharmacology & Drug Discovery
NoteFor research use only
Expiration Date12 months from date of receipt.
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