(Sar1,Ile4,8)-Angiotensin II

SKU: orb1980809

Description

(Sar1,Ile4,8)-Angiotensin II is a functionally selective AT1 receptor agonist that potentiates insulin signaling. It enhances insulin-stimulated Akt and GSK3α/β phosphorylation, promoting glycogen synthesis. This peptide is a valuable research tool for studying metabolic cross-talk in conditions like insulin resistance, applicable in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: RAAS
• CAS Number: 185461-45-4
• MW: 918.14
• Formula: C₄₃H₇₅N₁₃O₉
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

101008474