[Sar1, Ile8]-Angiotensin II acetate

SKU: orb1299693

Description

This research compound, [Sar1, Ile8]-Angiotensin II acetate, is a potent AT1 receptor agonist that activates vascular NAD(P)H oxidases to stimulate superoxide anion production. It is widely used in vitro and in vivo to study angiotensin II-mediated oxidative stress, hypertension, and vascular smooth muscle cell pathophysiology.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• Target: RAAS
• MW: 1028.2
• Purity: 99.36% (May vary between batches)
• Formula: C₄₈H₇₇N₁₃O₁₂
• SMILES: CC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC)=O)CCC/N=C(N)\N)=O)C(C)C)=O)CC1=CC=C(O)C=C1)=O)C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(O)=O)[C@H](CC)C)=O)=O)CC3=CN=CN3)=O)C.CC(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

angiotensin II receptor, [Sar1, Ile8] Angiotensin II acetate, [Sar1, Ile8]Angiotensin II acetate, [Sar1, Ile8]-Angiotensin II Acetate, [Sar-1, Ile8]-Angiotensin II acetate(37827-06-8 free base)

Compound Identifiers

PubChem CID

168013308