SAP15

SKU: orb2563636

Description

SAP15 is a cell-penetrating synthetic peptide derived from human beta-defensin 3, exhibiting anti-inflammatory activity by inhibiting HDAC5 and NF-κB p65 phosphorylation. It is used in research on inflammation regulation, biomaterials, and osteoarthritis models, showing efficacy in reducing inflammatory markers in LPS-stimulated macrophages and chondrocytes.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• Target: NF-κB,HDAC
• CAS Number: 1403753-45-6
• MW: 1767.16
• Formula: C₆₈H₁₃₁N₃₁O₁₈S₃
• SMILES: [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC(CN)=O)=O)CS)=O)CO)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CS)=O)CS)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)CCCNC(=N)N

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171714378