Sanguinarine chloride

SKU: orb1310909

Description

Sanguinarine chloride, a benzophenanthridine alkaloid, induces apoptotic cell death through the generation of reactive oxygen species (ROS). This small molecule is utilized in research areas such as cancer biology and toxicology, with applications in both in vitro cell culture studies and in vivo experimental models.

Research Area

Cardiovascular Research, Cell Biology, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 5578-73-4
• MW: 367.78
• Purity: 99.41%
• Formula: C₂₀H₁₄ClNO₄
• SMILES: [Cl-].C[n+]1cc2c3OCOc3ccc2c2ccc3cc4OCOc4cc3c12
• Target: Autophagy,Antibacterial,Parasite,EGFR,VEGFR,Apoptosis
• Solubility: DMSO:3.68 mg/mL (10.01 mM)

Bioactivity

• Target IC50:
  PP2C:0.68 μM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, Bacterial, Apoptosis, Inhibitor, Egr-1, Parasite, inhibit, Pseudochelerythrine, Pseudochelerythrine chloride, Pseudochelerythrine Chloride, Sanguinarin, Sanguinarine, Sanguinarine Chloride, Sanguinarine chloride, Sanguinarium, Sanguinarium Chloride, Sanguinarium chloride, VEGFR

Compound Identifiers

PubChem CID

68635