Sanggenon D

SKU: orb1689927

Description

Sanggenon D is a bioactive flavonoid from Morus alba bark that acts as a GABA(A) receptor modulator. It exhibits antioxidant and antibacterial properties, inhibiting Staphylococcus aureus growth by targeting fatty acid biosynthesis and suppressing breast cancer cell proliferation in vitro.

Research Area

Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 81422-93-7
• MW: 708.71
• Purity: 99.92% (May vary between batches)
• Formula: C₄₀H₃₆O₁₂
• SMILES: CC(C)=CCC12Oc3cc(O)ccc3C1(O)Oc1cc(O)c(C3C=C(C)CC(C3C(=O)c3ccc(O)cc3O)c3ccc(O)cc3O)c(O)c1C2=O
• Target: GABA Receptor,Antibiotic,Lipase
• Solubility: DMSO:50 mg/mL (70.55 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.82 mM)

Bioactivity

• In Vitro:
  Using tyrosine as substrate, the inhibitory activity of sanggenon D against tyrosinase was determined at 30 and 100 μM, with an IC50 value of 7.3 μM.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sanggenon D, Sanggenone D, Antibiotic, COX, NO, NOS, GABAA, GABA Receptor, GABAReceptor

Compound Identifiers

PubChem CID

13824422