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Catalog Number | orb1689927 |
---|---|
Category | Small Molecules |
Description | Sanggenon D |
CAS Number | 81422-93-7 |
Purity | 98% |
MW | 708.71 |
SMILES | C(C=C(C)C)C12C(O)(C=3C(O1)=CC(O)=CC3)OC=4C(C2=O)=C(O)C(=C(O)C4)C5C(C(=O)C6=C(O)C=C(O)C=C6)C(CC(C)=C5)C7=C(O)C=C(O)C=C7 |
Formula | C40H36O12 |
Biological Activity | Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 cells at > 10 uM; inhibition of nitric oxide production was mediated by suppression of iNOS enzyme induction but not by direct inhibition of iNOS enzyme activity. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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