Salvinorin A Propionate

• Catalog Number: orb1692350
• Category: Small Molecules
• Description: Salvinorin A Propionate
• Purity: 98.00%
• MW: 446.49
• Biological Activity: Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over μ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 μg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A .
• CAS Number: 689295-71-4
• Formula: C₂₄H₃₀O₈
• SMILES: C[C@@]12[C@@]3([C@](C)([C@H](C(OC)=O)C[C@H](OC(CC)=O)C3=O)CC[C@]1(C(=O)O[C@@H](C2)C=4C=COC4)[H])[H]
• Storage: -20°C
• Note: For research use only