Salicylanilide

SKU: orb1223789

Description

Salicylanilides are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.(In Vitro):Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 87-17-2
• MW: 213.24
• Purity: >98% (HPLC)
• Formula: C₁₃H₁₁NO₂
• SMILES: O=C(NC1=CC=CC=C1)C2=CC=CC=C2O
• Target: Reverse Transcriptase
• Solubility: Ethanol: 18 mg/mL (84.41 mM); DMSO: 43 mg/mL (201.66 mM)

Bioactivity

• In Vitro:
  Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Salicylanilide

Quick Database Links

Gene Symbol

Reverse Transcriptase