Salicin

SKU: orb1310611

Description

Salicin, a natural phenol β-glycoside derived from willow bark, is a research compound with established anti-inflammatory properties. It is widely used in pharmacological studies, including in vitro enzyme assays and in vivo models of inflammation, to investigate its mechanism of action and therapeutic potential.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 138-52-3
• MW: 286.28
• Purity: 98.79%
• Formula: C₁₃H₁₈O₇
• SMILES: O([C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=C(CO)C=CC=C2
• Target: COX,Endogenous Metabolite
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:22 mg/mL (76.85 mM);DMSO:50 mg/mL (174.65 mM)

Bioactivity

• In Vivo:
  Salicin is a prodrug that is gradually transported to the lower intestine where it is metabolized by intestinal bacteria into saligenin, which is then absorbed by the body and further converted into salicylic acid. Thus, it can exert antipyretic effects without causing gastric damage.

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, D-(−)-Salicin, Salicin, Salicine, Salicoside

Compound Identifiers

PubChem CID

439503