sAJM589

SKU: orb1706666

Description

sAJM589

Research Area

Cell Biology

Key Properties

• CAS Number: 2089-82-9
• MW: 246.26
• Formula: C₁₆H₁₀N₂O
• SMILES: OC=1C=C2N=C3C=CC=CC3=NC2=C4C=CC=CC14
• Target: c-Myc
• Solubility: DMSO:4 mg/mL (16.24 mM)

Bioactivity

• Target IC50:
  MYC:1.8 μM
• In Vitro:
  sAJM589 inhibits cell proliferation of multiple Myc-dependent cancer cell lines and anchorage-independent growth of Raji cells; sAJM589 effectively disrupts Myc-Max heterodimers to reduce Myc protein levels in a dose-dependent manner with an IC50 of 1.8 μM.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Myc, Benzo[a]phenazin-5-ol, cMyc, 5-Hydroxybenzo[a]phenazine, sAJM 589, sAJM589, sAJM-589

Compound Identifiers

PubChem CID

135480579