Saikosaponin D

SKU: orb1303573

Description

Saikosaponin D is a novel SERCA inhibitor that protects against acetaminophen-induced hepatotoxicity by suppressing NF-κB and STAT3 signaling pathways. It is a valuable research tool for studying liver injury, calcium homeostasis, and inflammation in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 20874-52-6
• MW: 780.98
• Purity: 99.73% (May vary between batches)
• Formula: C₄₂H₆₈O₁₃
• SMILES: CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC35OCC6(CCC(C)(C)CC36)C(O)CC45C)C2(C)CO)C(O)C(OC2OC(CO)C(O)C(O)C2O)C1O
• Target: NF-κB,Estrogen Receptor/ERR,Antibacterial,STAT
• Solubility: DMSO:262 mg/mL (335.48 mM);H2O:insoluble

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Inhibitor, ERR, EstrogenReceptor, Estrogen Receptor/ERR, Estrogen Receptor, inhibit, NF-kB, NFkB, NF-κB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB, Saikosaponin D, STAT, STAT3

Compound Identifiers

PubChem CID

4483645