Saikosaponin B1

SKU: orb1303574

Description

This orally active saponin compound functions as an activator, stimulating the release of Prostaglandin E2 in vitro and demonstrating anti-inflammatory activity in both in vitro and in vivo experimental models. It is a useful research tool for studying inflammation pathways and eicosanoid signaling.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 58558-08-0
• MW: 780.98
• Purity: 99.70% (May vary between batches)
• Formula: C₄₂H₆₈O₁₃
• SMILES: CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC3=C5CC(C)(C)CCC5(CO)C(O)CC43C)C2(C)CO)C(O)C(OC2OC(CO)C(O)C(O)C2O)C1O
• Target: Others,TNF,Hedgehog/Smoothened,STAT,Smo,Interleukin
• Solubility: DMSO:50 mg/mL (64.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (12.8 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Saikosaponin B 1, Saikosaponin B1, Saikosaponin B-1, Smoothened, Smo, tumor growth, Inhibitor, Hedgehog signaling pathway, medulloblastoma, inhibit, anticancer

Compound Identifiers

PubChem CID

14798494