Saikosaponin A

SKU: orb1305044

Description

Saikosaponin A is a bioactive small molecule with broad pharmacological activities, including neuroprotective, anti-inflammatory, and immunomodulatory effects. Research demonstrates its efficacy in attenuating neuropathic pain in CCI rat models by inhibiting spinal p38 MAPK/NF-κB pathways, NMDA currents, and pro-inflammatory cytokine production, supporting its use in neuroscience and immunology research.

Research Area

Infectious Disease & Virology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 20736-09-8
• MW: 780.98
• Purity: 99.88% (May vary between batches)
• Formula: C₄₂H₆₈O₁₃
• SMILES: [H][C@@]12CC(C)(C)CC[C@@]11CO[C@@]22C=C[C@]3([H])[C@@]4(C)CC[C@H](O[C@]5([H])O[C@H](C)[C@H](O)[C@H](O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H]5O)[C@@](C)(CO)[C@]4([H])CC[C@@]3(C)[C@]2(C)C[C@@H]1O
• Target: Liver X Receptor,NF-κB,Antibacterial
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.56 mM);H2O:Insoluble;DMSO:50 mg/mL (64.02 mM);Ethanol:30 mg/mL (38.41 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Saikosaponin A, NF-κB, NFκB, NFkB, NF-kB, LXR, inhibit, Liver X receptor, Liver X Receptor, LiverXReceptor, Inhibitor, Bacterial

Compound Identifiers

PubChem CID

167928