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SAH-EZH2

SKU: orb1679238

Description

This small molecule inhibitor disrupts the EZH2/EPP interaction with a Kd of 320 nM, leading to reduced EZH2 expression and H3K27me3 by the PRC2 complex. It halts proliferation and promotes monocyte-to-macrophage differentiation in MLL-AF9 leukemia models, supporting research into epigenetic therapies for hematological cancers.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

TargetHistone Methyltransferase
Molecular Weight3432.05

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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SAH-EZH2 (orb1679238)

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