Sacubitril/Valsartan

SKU: orb1305702

Description

Sacubitril/Valsartan

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 936623-90-4
• MW: 957.99
• Purity: 99.94%
• Formula: C₄₈H₅₅N₆O₈Na₃.2.5H₂O
• SMILES: CC(C)[C@@H](C([O-])=O)N(C(CCCC)=O)CC1=CC=C(C=C1)C2=C(C3=NN=N[N-]3)C=CC=C2.CCOC([C@H](C)C[C@H](NC(CCC([O-])=O)=O)CC4=CC=C(C5=CC=CC=C5)C=C4)=O.[Na+].O.[Na+].[Na+].O
• Target: Apoptosis,RAAS,Neprilysin
• Solubility: DMSO:45.45 mg/mL (47.44 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.09 mM);H2O:92 mg/mL (96.03 mM);Ethanol:9 mg/mL (9.39 mM)

Bioactivity

• In Vitro:
  LCZ696 is a single molecule that is comprised of molecular moieties of valsartan, an ARB, and AHU377, a neprilysin inhibitor (1:1 ratio).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Angiotensin Receptor, angiotensin, ARN, Apoptosis, Cluster of differentiation 10, CD10, Neprilysin, Neutral endopeptidase, LCZ696, LCZ-696, LCZ 696, heart, Valsartan, Sacubitril mixture with Valsartan, Sacubitril/Valsartan, Sacubitril, RAAS, receptor-neprilysin

Compound Identifiers

PubChem CID

171344547