Sacubitril Enantiomer

SKU: orb1307133

Description

Sacubitril Enantiomer (AHU377 Isomer 2) is the opposite-handed stereoisomer of the neprilysin (NEP) inhibitor Sacubitril. This compound is used in research to study the stereospecific effects of NEP inhibition in cardiovascular and metabolic disease models, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 430.53
• Purity: 99.89% (May vary between batches)
• Formula: C₂₄H₂₈NO₅ 1/2Ca
• SMILES: O=C([O-])CCC(N[C@H](C[C@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O.O=C([O-])CCC(N[C@H](C[C@H](C)C(OCC)=O)CC3=CC=C(C4=CC=CC=C4)C=C3)=O.[Ca+2]
• Target: Others
• Solubility: DMSO:55 mg/mL (127.75 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2R,4S-Sacubitril, ahu377 isomer 2, Sacubitril Enantiomer

Compound Identifiers

PubChem CID

137966096