S65487 sulfate

SKU: orb1690853

Description

S65487 (VOB560) sulfate is a potent, selective Bcl-2 inhibitor active against mutations like G101V and D103Y, with minimal affinity for MCL-1, BFL-1, and BCL-XL. It induces apoptosis and demonstrates anticancer activity in research models, applicable for studying hematological malignancies in both in vitro and in vivo experimental settings.

Research Area

Cell Biology

Key Properties

• CAS Number: 2416937-01-2
• MW: 815.34
• Formula: C₄₁H₄₃ClN₆O₈S
• SMILES: OS(O)(=O)=O.Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1
• Target: Apoptosis,Others,Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162642598