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S58 aptamer

SKU: orb3210442

Description

The S58 aptamer is a single-stranded DNA aptamer that targets the transforming growth factor-β receptor II (TGF-βRII). It inhibits the interaction between TGF-βRII and TGF-β. Additionally, the S58 aptamer enhances the surgical outcomes of glaucoma filtration surgery (GFS) by activating the intracellular antioxidant defense system via the PI3K/Akt/Nrf2 signaling pathway.

Images & Validation

Key Properties

TargetTGF-beta/Smad,Nrf2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information