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S55746 hydrochloride

SKU: orb1708597

Description

S55746 hydrochloride is a potent, orally bioavailable, and selective BCL-2 inhibitor with low nanomolar affinity (Ki=1.3 nM). It demonstrates antitumor efficacy in preclinical in vivo models with a favorable toxicity profile, making it a valuable tool for oncology research targeting apoptosis pathways.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1448525-91-4
MW747.28
FormulaC43H43ClN4O6
SMILESCl.Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1
TargetBcl-2 Family

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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S55746 hydrochloride (orb1708597)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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