S39625

SKU: orb1699422

Description

S39625 is a stable, potent, and selective topoisomerase I inhibitor that evades drug efflux transporters. It induces persistent DNA damage (γ-H2AX) and Top1 cleavage complexes at nanomolar concentrations, demonstrating potent antiproliferative activity in cancer cell lines, supporting its investigation as an anticancer agent in both in vitro and in vivo research.

Research Area

Molecular Biology

Key Properties

• CAS Number: 536711-20-3
• MW: 430.45
• Formula: C₂₅H₂₂N₂O₅
• SMILES: O=C1N2CC=3C(C2=CC4=C1CC(=O)C4(CC)O)=NC=5C(C3C6CCC6)=CC7=C(C5)OCO7
• Target: Topoisomerase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

22745042