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S1R agonist 2 hydrochloride

SKU: orb1944653

Description

Compound 8b hydrochloride is a potent and selective sigma-1 receptor (S1R) agonist, exhibiting high affinity for S1R (Ki = 1.1 nM) over S2R. It has demonstrated neuroprotective properties in vitro against oxidative stress and excitotoxicity, making it a valuable tool for studying neuroprotection and neurodegenerative disease mechanisms.

Research Area

Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

MW345.91
FormulaC21H28ClNO
TargetSigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

S1R agonist 2 hydrochloride (orb1944653)

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