S100P-IN-1

SKU: orb1687508

Description

S100P-IN-1 is a potent small molecule inhibitor of the S100P protein. It demonstrates anti-metastatic activity against pancreatic cancer cells in vitro, making it a valuable research tool for studying metastasis and S100P-related pathways in oncology.

Research Area

Signal Transduction

Key Properties

• CAS Number: 690991-06-1
• MW: 440.4
• Purity: 99.93% (May vary between batches)
• Formula: C₂₅H₁₆N₂O₆
• SMILES: O=C(O)C1=CC=CC(=C1)N2C(=O)C3C4C=5C=CC=CC5C(C=6C=CC=CC64)(N(=O)=O)C3C2=O
• Target: Others
• Solubility: DMSO:80 mg/mL (181.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.49 mM)

Bioactivity

• Target IC50:
  S100P:22.7 nM
• In Vitro:
  S100P-IN-1 (Compound 4) inhibits the binding of S100P to RAGE in a dose-dependent manner. S100P-IN-1 (10 µM, 24 hours) specifically inhibits S100P-mediated cell invasion without apparent cytotoxicity.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S100P

Compound Identifiers

PubChem CID

2936550