(S)-Sabutoclax

SKU: orb2283544

Description

(S)-Sabutoclax is an optically active pan-inhibitor of antiapoptotic Bcl-2 family proteins, effectively displacing BH3 peptides from Bcl-XL, Bcl-2, Mcl-1, and Bfl-1. It demonstrates potent, sub-micromolar growth inhibition in various cancer cell lines and is a key research tool for studying apoptosis in both in vitro and in vivo cancer models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1228178-73-1
• MW: 732.84
• Formula: C₄₂H₄₂N₂O₈S
• SMILES: CC1=CC2=C(C(NC[C@@H](C3=CC=CC=C3)C)=O)C(O)=C(O)C=C2C(O)=[C@]1[C@]4=C(C)C=C5C(C(NC[C@@H](C6=CC=CC=C6)C)=O)=C(O)C(O)=CC5=C4O
• Target: Bcl-2 Family,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44224066