(S)-PI3K-IN-2

SKU: orb3028490

Description

(S)-PI3K-IN-2 is the enantiomer of PI3K-IN-2, functioning as a ΡΙ3Κβ/δ inhibitor with IC50 values of 0.198 and 0.282 μM, respectively. It can also inhibit the phosphorylation of AKT(ser473) in MDA-MB-468 cells, with an IC50 of 27 nM.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1403458-27-4
• MW: 525.544
• Formula: C₂₈H₂₉F₂N₃O₅
• SMILES: C(=O)(C1=CC(=C2C(=C1)C(=O)C=C(O2)N3CCOCC3)[C@H]4N(CCC4)C5=CC(F)=CC(F)=C5)N6CCOCC6
• Target: PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PI3K