(S)-ML753286

SKU: orb1710298

Description

(S)-ML753286 is a potent and selective inhibitor of the Breast Cancer Resistance Protein (BCRP/ABCG2) efflux transporter, exhibiting an IC50 of 0.6 µM. It is a valuable chemical probe used in vitro and in vivo to investigate BCRP-mediated multidrug resistance in cancer and to study drug transport at biological barriers.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1699720-85-8
• MW: 355.43
• Formula: C₂₀H₂₅N₃O₃
• SMILES: [H][C@@]12Cc3c([nH]c4cc(OC)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](C)NC2=O
• Target: BCRP,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91669184