S-methyl DM1

SKU: orb1708611

Description

S-methyl DM1 is a thiomethyl derivative of the cytotoxic agent Maytansine, functioning as a potent tubulin-binding inhibitor with a Kd of 0.93 µM to disrupt microtubule assembly. This activity makes it a valuable tool compound for investigating antimitotic mechanisms and cytotoxicity in cancer cell biology research, both in vitro and in preclinical models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 912569-84-7
• MW: 752.31
• Formula: C₃₆H₅₀ClN₃O₁₀S
• SMILES: C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCSC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
• Target: Microtubule Associated,ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

89629084