(S)-(+)-Ibuprofen

SKU: orb1310605

Description

Dexibuprofen, the (S)-enantiomer of ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID) that functions as a cyclooxygenase (COX) inhibitor. It is widely used in pharmacological research to study inflammation, pain, and fever mechanisms in both in vitro enzyme assays and in vivo animal models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 51146-56-6
• MW: 206.28
• Purity: 99.51%
• Formula: C₁₃H₁₈O₂
• SMILES: CC(C)CC1=CC=C(C=C1)[C@H](C)C(O)=O
• Target: Thrombin,PPAR,COX,Bcl-2 Family,Cysteine Protease
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.7 mM);DMSO:25 mg/mL (121.19 mM)

Bioactivity

• Target IC50:
  COX-1:13 μM|COX-2:370 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S(+)-enantiomer|thrombomodulin|PPARγ|inhibit|NF-κB|Inhibitor|Ibuprofen|analgesic|anti-inflammatory|antipyretic|Bcl-2|(S) (+) Ibuprofen|(S)(+)Ibuprofen|(S)-Ibuprofen|CysteineProtease|Cysteine Protease|Cystic fibrosis transmembrane conductance regulator|Cyclooxygenase|Dexibuprofen|COX|COX-1|COX-2

Compound Identifiers

PubChem CID

39912