(S)-Enitociclib

SKU: orb1739092

Description

(S)-Enitociclib (VIP152) is a potent and selective CDK9 inhibitor that suppresses RNA polymerase II-driven transcription, leading to the downregulation of pro-survival proteins and complete regression of MYC-driven lymphomas in vivo. Its application extends to oncology research, particularly in studying transcription-dependent cancers, with efficacy demonstrated in both cellular and animal models.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 1610408-97-3
• MW: 404.43
• Purity: 98.98%
• Formula: C₁₉H₁₈F₂N₄O₂S
• SMILES: COC1=C(C2=C(F)C=NC(NC3=CC(C[S@@](C)(=N)=O)=CC=N3)=C2)C=CC(F)=C1
• Target: CDK,Others,Apoptosis,DNA/RNA Synthesis

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CDK9, BMS986126, BMS 986126, VIP 152, VIP152, VIP-152

Compound Identifiers

PubChem CID

139593425