(S)-BI-1001

SKU: orb1706673

Description

(S)-BI-1001 is the pharmacologically active S-enantiomer of BI-1001, functioning as an HIV-1 integrase inhibitor. It demonstrates antiviral activity with an IC50 of 28 nM and an EC50 of 450 nM in vitro, and binds with a Kd of 4.7 µM. This compound is a valuable research tool for studying HIV replication mechanisms and antiviral drug development.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 957889-73-5
• MW: 420.68
• Formula: C₁₉H₁₅BrClNO₃
• SMILES: [C@H](C(O)=O)(OC)C1=C(C2=C(N=C1C)C=CC(Br)=C2)C3=CC=C(Cl)C=C3
• Target: HIV Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24800073