(S)-5-hydroxy-6-methoxy Duloxetine maleate

SKU: orb1979977

Description

(S)-5-Hydroxy-6-methoxy Duloxetine is an active (S)-duloxetine metabolite formed via CYP1A2/CYP2D6. It acts as a triple monoamine reuptake inhibitor, blocking human SERT, NET, and DAT with Kis of 266, 920, and 2,814 nM, respectively. This compound is a valuable research tool for in vitro neuropharmacology studies of transporter inhibition.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 459.51
• Formula: C₁₉H₂₁NO₃S.C₄H₄O₄
• SMILES: OC(/C=C\C(O)=O)=O.CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C(O)C(OC)=CC=C32
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361404