Ryuvidine

SKU: orb1704118

Description

Ryuvidine is a small molecule dual inhibitor of KDM5A and SETD8, inducing DNA damage response and inhibiting H4K20 methylation. It has demonstrated anticancer activity in breast cancer and erythroplasia research models, showing efficacy in both in vitro and in vivo experimental settings.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 265312-55-8
• MW: 284.33
• Purity: 98.60% (May vary between batches)
• Formula: C₁₅H₁₂N₂O₂S
• SMILES: Cc1nc2c(s1)C(=O)C=C(Nc1ccc(C)cc1)C2=O
• Target: Histone Demethylase|||Histone Methyltransferase|||CDK
• Solubility: DMF:2 mg/mL (7.03 mM);DMSO:1 mg/mL (3.52 mM)

Bioactivity

• Target IC50:
  CDK4:6.0 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CDK4, KDM5A, Histone Demethylase, HistoneMethyltransferase, HistoneDemethylase, Histone Methyltransferase, SETD8, Ryuvidine

Compound Identifiers

PubChem CID

481747