RWJ-58643 HCl

SKU: orb1741006

Description

RWJ-58643 is a reversible inhibitor of beta-tryptase and trypsin. In research, a low dose combined with budesonide reduced allergic inflammation markers in vivo, while higher doses paradoxically increased IL-5 and eosinophilia, making it a tool for studying mast cell and protease functions.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 287182-52-9
• MW: 482.984
• Formula: C₂₀H₂₇ClN₆O₄S
• SMILES: C(C(NC(=O)[C@H]1N(C(C)=O)C[C@H](O)C1)CCCNC(=N)N)(=O)C2=NC=3C(S2)=CC=CC3.Cl
• Target: Others,Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171360755