RUNX-IN-2

SKU: orb2277780

Description

RUNX-IN-2 is a covalent small molecule inhibitor that selectively alkylates RUNX-binding DNA sequences. This activity disrupts RUNX function, leading to inhibition of cancer cell proliferation and p53-dependent apoptosis, as demonstrated in both in vitro assays and in vivo PANC-1 xenograft models.

Research Area

Cell Biology

Key Properties

• CAS Number: 2893777-88-1
• MW: 1524.52
• Formula: C₇₁H₈₈Cl₂N₂₄O₁₁
• SMILES: N(C(=O)C1=NC(NC(=O)C2=NC(NC(CCNC(CCCC3=CC=C(N(CCCl)CCCl)C=C3)=O)=O)=CN2C)=CN1C)C=4C=C(C(NC=5N=C(C(NCCCC(NC=6C=C(C(NC=7C=C(C(NC=8C=C(C(NC=9C=C(C(NCCCN(C)C)=O)N(C)C9)=O)N(C)C8)=O)N(C)C7)=O)N(C)C6)=O)=O)N(C)C5)=O)N(C)C4
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510607