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RTI-122 dihydrochloride

SKU: orb3210878

Description

RTI-122 dihydrochloride is a GPR88 agonist capable of crossing the blood-brain barrier. It activates the GPR88-mediated G protein signaling pathway by enhancing cAMP accumulation and GTPγS binding activity. RTI-122 dihydrochloride reduces binge-like drinking, alcohol intake, operant alcohol self-administration, and the motivation to consume alcohol in rodents, while also inhibiting relapse into alcohol-seeking behavior. This compound is used in research related to alcohol use disorder.

Images & Validation

Key Properties

TargetGPCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information