You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1303961 |
---|---|
Category | Small Molecules |
Description | RSL3 |
CAS Number | 1219810-16-8 |
Purity | 99.96% |
MW | 440.88 |
SMILES | C(CCl)(=O)N1[C@H](C2=C(C=3C(N2)=CC=CC3)C[C@@H]1C(OC)=O)C4=CC=C(C(OC)=O)C=C4 |
Formula | C23H21ClN2O5 |
Biological Activity | RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of iron death that is selective for tumor cells carrying oncogenic RAS. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Filter by Rating