RSK2/TOP2-IN-1

SKU: orb3173184

Description

RSK2/TOP2-IN-1 is a dual inhibitor targeting RSK2 and TOP2 enzymes. It specifically targets critical enzymes related to tumor progression, including ribosomal S6 kinase (RSK2) and topoisomerases (TOP2) IIα/IIβ. The compound demonstrates a selectivity index greater than 2 across all squamous cell carcinoma (SCC) cell lines. RSK2/TOP2-IN-1 induces apoptosis, autophagy, and the production of reactive oxygen species (ROS). It is applicable in cancer research, particularly for squamous cell carcinoma.

Research Area

Cell Biology, Immunology & Inflammation, Molecular Biology, Signal Transduction

Key Properties

• Target: Autophagy,Topoisomerase,ROS,Apoptosis,S6 Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Autophagy,Topoisomerase,ROS,Apoptosis,S6 Kinase