RS47

SKU: orb3027396

Description

RS47 (Compound 1a) is a small molecule (Kd = 1.1 μM) that specifically targets RelB, selectively inhibiting the non-canonical NF-κB pathway by disrupting RelB binding to target DNA. It exhibits antitumour activity in vivo and in vitro and may be used in studies of colorectal cancer and B-cell lymphoma.

Research Area

Signal Transduction

Key Properties

• CAS Number: 301655-16-3
• MW: 354.43
• Purity: 98.76% (May vary between batches)
• Formula: C₁₈H₁₈N₄O₂S
• SMILES: OC1=CC=C(O)C(=C1)C(=NNC=2N=CN=C3SC4=C(C32)CCCC4)C
• Target: Others,NF-κB
• Solubility: DMSO:20 mg/mL (56.43 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RS-47, RS 47

Quick Database Links

Gene Symbol

Others,NF-κB