(R,S)-Ivosidenib

SKU: orb1708137

Description

Ivosidenib is a targeted inhibitor of mutant IDH1 used in research for acute myeloid leukemia (AML). The (R,S)-enantiomer is the less active form of this compound, serving as a useful control in both in vitro enzymatic assays and in vivo xenograft studies to elucidate the specific effects of the active drug.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2070009-31-1
• MW: 582.96
• Formula: C₂₈H₂₂ClF₃N₆O₃
• SMILES: Fc1cncc(c1)N([C@@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)C(=O)[C@@H]1CCC(=O)N1c1cc(ccn1)C#N
• Target: Isocitrate Dehydrogenase (IDH),Opioid Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121230976