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RS-25344

SKU: orb1298254

Description

RS-25344 is a selective PDE4 inhibitor used in research to study inflammatory processes and sperm physiology. In vitro, it suppresses eosinophil migration and enhances spermatozoa motility, making it a tool for investigating asthma, COPD, and male fertility.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number152814-89-6
MW375.34
Purity99.02%
FormulaC19H13N5O4
SMILESO=C1N(C=2C(C(=O)N1CC=3C=CN=CC3)=CC=CN2)C4=CC(N(=O)=O)=CC=C4
TargetPDE
SolubilityDMSO:50 mg/mL (133.21 mM)

Bioactivity

Target IC50
PDE2:160 nM|PDE3:330 nM|PDE4:0.28 nM|PDE1:100 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

RS 25344, RS25344, RS-25344, PDE4, PDE3, PDE2, PDE1

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

RS-25344 (orb1298254)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 120.00
5 mg
$ 230.00
1 ml x 10 mM (in DMSO)
$ 240.00
10 mg
$ 320.00
25 mg
$ 490.00
50 mg
$ 670.00
100 mg
$ 900.00
200 mg
$ 1,170.00
DispatchUsually dispatched within 3-5 working days
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