RPR-200765A Mesylayte

SKU: orb1739649

Description

RPR-200765A is a potent, selective p38 MAPK inhibitor (IC50=50 nM) that suppresses TNFα release in vitro (EC50=110 nM in human monocytes) and in vivo (ED50=6 mg/kg in mice). It demonstrates oral efficacy in rat arthritis models, suggesting potential disease-modifying activity for rheumatoid arthritis research.

Key Properties

• CAS Number: 218162-38-0
• MW: 452.48
• Formula: C₂₄H₂₅FN₄O₄
• SMILES: CS(O)(=O)=O.C[C@@]1(CO[C@@H](OC1)c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1)C(=O)N1CCOCC1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9828951