Rp-dGTPαS

• Catalog Number: orb2283566
• Category: Small Molecules
• Description: Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates.
• Target: Others
• MW: 523.25
• CAS Number: 80902-29-0
• Formula: C₁₀H₁₆N₅O₁₂P₃S
• SMILES: O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)S)[C@@H](O)C3)NC(N)=N1
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.