Rotundic acid

SKU: orb1301339

Description

Rotundic acid is a natural triterpenoid with demonstrated cytotoxic activity against multiple human cancer cell lines, including HepG2, A375, NCI-H446, MCF-7, and HT-29. It is a research tool for studying anticancer mechanisms in vitro and has shown preliminary bioactivity in some in vivo models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 20137-37-5
• MW: 488.70
• Purity: 99.97% (May vary between batches)
• Formula: C₃₀H₄₈O₅
• SMILES: [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@](C)(O)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)[C@@]2(C)CO
• Target: p38 MAPK,Apoptosis,mTOR,Akt
• Solubility: 10% DMSO+90% Corn Oil:2.50 mg/mL (5.12 mM);DMSO:245.00 mg/mL (501.33 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Akt, Apoptosis, inhibit, mTOR, Inhibitor, Mammalian target of Rapamycin, p38 MAPK, p38MAPK, PKB, Rutundic acid, Rotundic acid, Protein kinase B

Compound Identifiers

PubChem CID

12315075