Rosuvastatin Sodium

SKU: orb1686613

Description

Rosuvastatin Sodium is a potent, competitive HMG-CoA reductase inhibitor (IC50: 11 nM) that also blocks the hERG potassium channel (IC50: 195 nM). It is used in research to study statin effects on cholesterol biosynthesis and cardiac electrophysiology, including hERG trafficking and its interaction with Hsp70, in both cellular and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 147098-18-8
• MW: 503.52
• Purity: 99.96% (May vary between batches)
• Formula: C₂₂H₂₇FN₃NaO₆S
• SMILES: C(=C/[C@H](C[C@H](CC(O)=O)O)O)\C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2.[Na]
• Target: Potassium Channel,HMG-CoA Reductase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23684378