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ROS-ERS inducer 1

SKU: orb1983109

Description

ROS-ERS inducer 1 is a platinum-based N-heterocyclic carbene complex that triggers immunogenic cell death (ICD) via endoplasmic reticulum stress and reactive oxygen species. This mechanism promotes the emission of damage-associated molecular patterns (DAMPs), demonstrating potent anticancer activity in hepatocellular carcinoma (HCC) models, both in vitro and in vivo, surpassing the efficacy of cisplatin.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

MW840.35
FormulaC24H23F2I2N3Pt
TargetOthers,Reactive Oxygen Species

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information